KOR-1 rabbit pAb

Cat :A16784

KOR,A16784, 16784, OPRK1, Kappa-type opioid receptor, OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IHC,WB,ELISA
Reactivity

Mouse,Rat
Dilution

WB 1:500-2000 IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from mouse KOR-1. AA range:331-380
Alternative names

OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Other

OPRK1, Kappa-type opioid receptor
Mol.Wt (Da)

42645
Concentration

1 mg/ml