KPB2 rabbit pAb

Cat :A16788

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human, Mouse

  • Dilution

    WB 1:500-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of KPB2 at Human/Mouse

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized peptide derived from human KPB2

  • Uniprot No

    P46019

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010],

  • Other

    PHKA2 PHKLA PYK, KPB2

  • Mol.Wt (Da)

    135850

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images