LAX1 rabbit pAb

Cat :A16948

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Rat,Mouse
Dilution

WB 1:500-2000 ELISA 1:5000-20000
Storage

-20°C/1 year
Specificity

LAX1 Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from human protein . at AA range: 30-110
Uniprot No

Q8IWV1
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

function:Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.,induction:Up-regulated in T-cells following TCR engagement.,PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.,
Other

LAX1 LAX, Lymphocyte transmembrane adapter 1 (Linker for activation of X cells) (Membrane-associated adapter protein LAX)
Concentration

1 mg/ml