LRP6 (phospho-Ser1490) rabbit pAb

Cat :A17139

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB
Reactivity

Human
Dilution

WB 1:1000-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of Human LRP6 (phospho-Ser1490)
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized phosho peptide around human LRP6 (Ser1490)
Uniprot No

O75581
Alternative names

Low-density lipoprotein receptor-related protein 6 (LRP-6)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

LDL receptor related protein 6(LRP6) Homo sapiens This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009],
Other

LRP6, LRP6 (Ser1490)
Concentration

1 mg/ml