MBD3 rabbit pAb

Cat :A17376

MBD,A17376, 17376, MBD3, Methyl-CpG-binding domain protein 3, MBD3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse
Dilution

WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

MBD3 Polyclonal Antibody detects endogenous levels of MBD3 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human MBD3. AA range:221-270
Uniprot No

O95983
Alternative names

MBD3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

methyl-CpG binding domain protein 3(MBD3) Homo sapiens DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],
Other

MBD3, Methyl-CpG-binding domain protein 3
Mol.Wt (Da)

32844
Concentration

1 mg/ml