Rabbit
IHC,WB
Human
IHC 1:50-200, WB 1:500-2000
-20°C/1 year
This antibody detects endogenous levels of human MCM7
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Synthesized peptide derived from human MCM7
P33993
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Polyclonal
IgG
minichromosome maintenance complex component 7(MCM7) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
MCM7 CDC47 MCM2, MCM7
1 mg/ml
Product | Reactivity | Applications | Conjugation | Catalog | Images |
---|