MEK Kinase-1 (phospho Thr1402) rabbit pAb

Cat :A17487

MEK,A17487, 17487, MAP3K1, Mitogen-activated protein kinase kinase kinase 1, MAP3K1; MAPKKK1; MEKK; MEKK1; Mitogen-activated protein kinase kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-MEK Kinase-1 (T1402) Polyclonal Antibody detects endogenous levels of MEK Kinase-1 protein only when phosphorylated at T1402.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human MAP3K1 around the phosphorylation site of Thr1402. AA range:1368-1417
Uniprot No

Q13233
Alternative names

MAP3K1; MAPKKK1; MEKK; MEKK1; Mitogen-activated protein kinase kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

mitogen-activated protein kinase kinase kinase 1(MAP3K1) Homo sapiens The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012],
Other

MAP3K1, Mitogen-activated protein kinase kinase kinase 1
Mol.Wt (Da)

161289
Concentration

1 mg/ml