MEK2 mouse mAb(2C3)

Cat :A17503

MEK,A17503, 17503, MAP2K2, Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2), MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protei

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Mouse
Applications

WB
Reactivity

Human,Rat,Mouse
Dilution

WB: 1:500 - 1:2000
Storage

-20°C/1 year
Specificity

MEK2 protein detects endogenous levels of MEK2
Source/Purification

The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from human MEK-2 around the non-phosphorylation site of T394.
Uniprot No

P36507
Alternative names

MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Monoclonal
Isotype

IgG
Background

mitogen-activated protein kinase kinase 2(MAP2K2) Homo sapiens The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008],
Other

MAP2K2, Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Concentration

1 mg/ml