MELK rabbit pAb

Cat :A17527

MELK ,A17527, 17527, MELK, Maternal embryonic leucine zipper kinase, MELK; KIAA0175; Maternal embryonic leucine zipper kinase; hMELK; Protein kinase Eg3; pEg3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,IF,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

MELK Polyclonal Antibody detects endogenous levels of MELK protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human MELK. AA range:431-480
Uniprot No

Q14680
Alternative names

MELK; KIAA0175; Maternal embryonic leucine zipper kinase; hMELK; Protein kinase Eg3; pEg3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.,PTM:Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with ZNF622 and PPP1R8.,tissue specificity:Expressed in placenta, kidney, thymus, testis, ovary and intestine.,
Other

MELK, Maternal embryonic leucine zipper kinase
Mol.Wt (Da)

74642
Concentration

1 mg/ml