mGluR-4 rabbit pAb

Cat :A17574

mGluR,A17574, 17574, GRM4, Metabotropic glutamate receptor 4, GRM4; GPRC1D; MGLUR4; Metabotropic glutamate receptor 4; mGluR4

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

mGluR-4 Polyclonal Antibody detects endogenous levels of mGluR-4 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human mGluR4. AA range:851-900
Uniprot No

Q14833
Alternative names

GRM4; GPRC1D; MGLUR4; Metabotropic glutamate receptor 4; mGluR4
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

glutamate metabotropic receptor 4(GRM4) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this
Other

GRM4, Metabotropic glutamate receptor 4
Mol.Wt (Da)

101868
Concentration

1 mg/ml