MKKS rabbit pAb

Cat :A17628

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB
Reactivity

Human, Mouse
Dilution

WB 1:500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of MKKS at Human/Mouse
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human MKKS
Uniprot No

Q9NPJ1
Alternative names

McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (Bardet-Biedl syndrome 6 protein)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.184% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],
Other

MKKS BBS6, MKKS
Concentration

1 mg/ml