MLK4 rabbit pAb

Cat :A17656

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

MLK4 Polyclonal Antibody detects endogenous levels of MLK4 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human MAP3KL4. AA range:631-680
Uniprot No

Q5TCX8
Alternative names

MLK4; KIAA1804; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,function:Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH3 domain.,subunit:Homodimer.,
Other

MLK4, Mitogen-activated protein kinase kinase kinase MLK4
Mol.Wt (Da)

113957
Concentration

1 mg/ml