Myosin Heavy Chain mouse mAb(11C2)

Cat :A18008

Price： ¥900¥1600

Size： 50ul 100ul

Source

Mouse
Applications

IF
Reactivity

Human,Mouse,R,FruitFly,Nematode
Dilution

IF: 1:100
Storage

-20°C/1 year
Specificity

The antibody detects endogenous MHC proteins.
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Synthetic Peptide of Myosin Heavy Chain
Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality

Monoclonal
Isotype

IgG
Background

Skeletal muscle Myosin or myosin II is the motor protein that generates force to drive muscle contraction. It is a 520 kDa hexamer comprised of two heavy chains and four light chains. Myosin heavy chain is 220 kDa in size and consists of a long coiled-coil domain tail that mediates dimerization of the two heavy chains and a globular head region that mediates ATP-dependent sliding of actin filaments. Myosin heavy chain can be proteolytically cleaved to produce heavy meromyosin, which includes the S1 motor domain (head region) and first third of the coiled coil domain, and light meromyosin, which includes the C-terminal two thirds of the coiled coil domain.
Concentration

1 mg/ml