Neuregulin-3 rabbit pAb

Cat :A18256

Neuregulin,A18256, 18256, NRG3, Pro-neuregulin-3 membrane-bound isoform, NRG3; Pro-neuregulin-3, membrane-bound isoform; Pro-NRG3

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse
Dilution

WB: 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Neuregulin-3 Polyclonal Antibody detects endogenous levels of Neuregulin-3 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human NRG3. AA range:311-360
Uniprot No

P56975
Alternative names

NRG3; Pro-neuregulin-3, membrane-bound isoform; Pro-NRG3
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

neuregulin 3(NRG3) Homo sapiens This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcri
Other

NRG3, Pro-neuregulin-3 membrane-bound isoform
Mol.Wt (Da)

77901
Concentration

1 mg/ml