Neurexin I rabbit pAb

Cat :A18258

Neurexin,A18258, 18258, NRXN1, Neurexin-1-alpha, NRXN1; KIAA0578; Neurexin-1-alpha; Neurexin I-alpha

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Neurexin I Polyclonal Antibody detects endogenous levels of Neurexin I protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human NRXN1. AA range:502-551
Uniprot No

Q9ULB1
Alternative names

NRXN1; KIAA0578; Neurexin-1-alpha; Neurexin I-alpha
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

NRXN1 (neurexin 1) encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for NRXN1 in the 3' region. Mutations in NRXN1 are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.
Other

NRXN1, Neurexin-1-alpha
Mol.Wt (Da)

161883
Concentration

1 mg/ml