NF-E4 rabbit pAb

Cat :A18306

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IHC,WB
Reactivity

Human
Dilution

IHC 1:50-200, WB 1:500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of human NF-E4
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human NF-E4
Uniprot No

Q86UQ8
Alternative names

Transcription factor NF-E4
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

nuclear factor, erythroid 4(NFE4) Homo sapiens The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],
Other

NFE4, NF-E4
Concentration

1 mg/ml