Nkx-2.8 rabbit pAb

Cat :A18425

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Nkx-2.8 Polyclonal Antibody detects endogenous levels of Nkx-2.8 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human NKX28. AA range:20-69
Uniprot No

Q8IUT7
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

NK2 homeobox 8(NKX2-8) Homo sapiens The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015],
Other

NKX2-8, Homeobox protein Nkx-2.8
Mol.Wt (Da)

25866
Concentration

1 mg/ml