NOD1 rabbit pAb

Cat :A18476

NOD,A18476, 18476, NOD1 CARD4, NOD1, Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4)

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB
Reactivity

Human, Mouse
Dilution

WB 1:500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of NOD1 at Human/Mouse
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human NOD1
Uniprot No

Q9Y239
Alternative names

Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.224% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009],
Other

NOD1 CARD4, NOD1
Concentration

1 mg/ml