P53 mouse mAb(PT0337)

Cat :A19337

Price： ¥900¥1600

Size： 50ul 100ul

Source

Mouse/IgG1, Kappa
Applications

IHC,WB
Reactivity

Human
Dilution

IHC 1:100-300，WB 1:500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of human P53
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human P53
Uniprot No

P04637
Alternative names

Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Monoclonal
Isotype

IgG
Background

tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],
Other

TP53 P53, P53
Concentration

1 mg/ml