p53 rabbit pAb

Cat :A19339

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB,IHC
Reactivity

Mouse,Rat
Dilution

WB: 1:1000-2000 IHC: 1:500-1000
Storage

-20°C/1 year
Specificity

The antibody detects endogenous p53 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthetic Peptide of p53
Uniprot No

P04637
Alternative names

TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality

Polyclonal
Isotype

IgG
Background

tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],
Other

TP53, Cellular tumor antigen p53
Concentration

1 mg/ml