PA26 rabbit pAb

Cat :A19396

PA26 ,A19396, 19396, SESN1, Sestrin-1, SESN1; PA26; SEST1; Sestrin-1; p53-regulated protein PA26

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

PA26 Polyclonal Antibody detects endogenous levels of PA26 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human SESN1. AA range:271-320
Uniprot No

Q9Y6P5
Alternative names

SESN1; PA26; SEST1; Sestrin-1; p53-regulated protein PA26
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

sestrin 1(SESN1) Homo sapiens This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
Other

SESN1, Sestrin-1
Mol.Wt (Da)

56557
Concentration

1 mg/ml