PAF-R rabbit pAb

Cat :A19413

PAF,A19413, 19413, PTAFR, Platelet-activating factor receptor, PTAFR; PAFR; Platelet-activating factor receptor; PAF-R; PAFr

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IF,ELISA
Reactivity

Human,Mouse,Rat
Dilution

IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

PAF-R Polyclonal Antibody detects endogenous levels of PAF-R protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human PTAFR. AA range:194-243
Uniprot No

P25105
Alternative names

PTAFR; PAFR; Platelet-activating factor receptor; PAF-R; PAFr
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

platelet activating factor receptor(PTAFR) Homo sapiens This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],
Other

PTAFR, Platelet-activating factor receptor
Mol.Wt (Da)

39203
Concentration

1 mg/ml