PATZ1 rabbit pAb

Cat :A19506

PATZ ,A19506, 19506, PATZ1 PATZ RIAZ ZBTB19 ZNF278 ZSG, PATZ1,

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB
Reactivity

Human
Dilution

WB 1：500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of PATZ1 at Human
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human PATZ1
Uniprot No

Q9HBE1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008],
Other

PATZ1 PATZ RIAZ ZBTB19 ZNF278 ZSG, PATZ1
Mol.Wt (Da)

75570
Concentration

1 mg/ml