PCNA mouse mAb(12D10)

Cat :A19571

Price： ¥900¥1600

Size： 50ul 100ul

Source

Mouse
Applications

WB,IF,IHC
Reactivity

Human,Rat,Mouse
Dilution

WB: 1:5000 IHC: 1:200 IF 1:200
Storage

-20°C/1 year
Specificity

The antibody detects endogenous PCNA protein.
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Synthetic Peptide of PCNA
Uniprot No

P12004
Alternative names

PCNA; Proliferating cell nuclear antigen; PCNA; Cyclin
Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Clonality

Monoclonal
Isotype

IgG
Background

proliferating cell nuclear antigen(PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],
Other

PCNA, Proliferating cell nuclear antigen
Mol.Wt (Da)

28769
Concentration

1 mg/ml