Perforin 1 rabbit pAb

Cat :A19698

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB 1:500-2000, IHC 1:50-200, ELISA 1:10000-20000
Storage

-20°C/1 year
Specificity

Perforin 1 Polyclonal Antibody detects endogenous levels of Perforin 1
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human PRF1. AA range:451-500
Uniprot No

P14222
Alternative names

Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

perforin 1(PRF1) Homo sapiens The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
Other

PRF1, Perforin 1
Mol.Wt (Da)

61377
Concentration

1 mg/ml