PGI2 synthase rabbit pAb

Cat :A19742

PGI2,A19742, 19742, PTGIS, Prostacyclin synthase, PTGIS; CYP8; CYP8A1; Prostacyclin synthase; Prostaglandin I2 synthase

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

PGI2 synthase Polyclonal Antibody detects endogenous levels of PGI2 synthase protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from the C-terminal region of human PGI2 synthase.
Uniprot No

Q16647
Alternative names

PTGIS; CYP8; CYP8A1; Prostacyclin synthase; Prostaglandin I2 synthase
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

prostaglandin I2 synthase(PTGIS) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008],
Other

PTGIS, Prostacyclin synthase
Mol.Wt (Da)

57104
Concentration

1 mg/ml