PKC α (phospho Thr638) rabbit pAb

Cat :A19896

PKCα,A19896, 19896, PRKCA, Protein kinase C alpha type, PRKCA; PKCA; PRKACA; Protein kinase C alpha type; PKC-A; PKC-alpha

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-PKC α (T638) Polyclonal Antibody detects endogenous levels of PKC α protein only when phosphorylated at T638.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human PKC alpha around the phosphorylation site of Thr638. AA range:606-655
Uniprot No

P17252
Alternative names

PRKCA; PKCA; PRKACA; Protein kinase C alpha type; PKC-A; PKC-alpha
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

protein kinase C alpha(PRKCA) Homo sapiens Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2
Other

PRKCA, Protein kinase C alpha type
Mol.Wt (Da)

76764
Concentration

1 mg/ml