PKC ε (phospho Ser729) rabbit pAb

Cat :A19912

PKC ε,A19912, 19912, PRKCE, Protein kinase C epsilon type, PRKCE; PKCE; Protein kinase C epsilon type; nPKC-epsilon

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-PKC ε (S729) Polyclonal Antibody detects endogenous levels of PKC ε protein only when phosphorylated at S729.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human PKC epsilon around the phosphorylation site of Ser729. AA range:688-737
Uniprot No

Q02156
Alternative names

PRKCE; PKCE; Protein kinase C epsilon type; nPKC-epsilon
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

protein kinase C epsilon(PRKCE) Homo sapiens Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macro
Other

PRKCE, Protein kinase C epsilon type
Mol.Wt (Da)

83674
Concentration

1 mg/ml