PMS2/PMS2CL rabbit pAb

Cat :A20039

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human
Dilution

IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

PMS2/PMS2CL Polyclonal Antibody detects endogenous levels of PMS2/PMS2CL protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human PMS2CL. AA range:125-174
Uniprot No

Q68D20/P54278
Alternative names

PMS2CL; Protein PMS2CL; PMS2-C terminal-like protein; PMS2; PMSL2; Mismatch repair endonuclease PMS2; DNA mismatch repair protein PMS2; PMS1 protein homolog 2
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,
Other

PMS2/PMS2CL, Mismatch repair endonuclease PMS2/Protein PMS2CL
Mol.Wt (Da)

20909
Concentration

1 mg/ml