PPP1R15B rabbit pAb

Cat :A20138

PPP1R15B ,A20138, 20138, PPP1R15B, Protein phosphatase 1 regulatory subunit 15B, PPP1R15B; Protein phosphatase 1 regulatory subunit 15B

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

PPP1R15B Polyclonal Antibody detects endogenous levels of PPP1R15B protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human PPP1R15B. AA range:411-460
Uniprot No

Q5SWA1
Alternative names

PPP1R15B; Protein phosphatase 1 regulatory subunit 15B
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

protein phosphatase 1 regulatory subunit 15B(PPP1R15B) Homo sapiens This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions, while the protein coding ORF is expressed at high levels in response to stress. Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress. In addition, it has been shown that this protein plays a role in membrane traffic that is independent of translation and that it is required for exocytosis from erythroleukemia cells. Allelic variants of this gene are associated with mi
Other

PPP1R15B, Protein phosphatase 1 regulatory subunit 15B
Mol.Wt (Da)

78430
Concentration

1 mg/ml