PSGL-1 rabbit pAb

Cat :A20291

PSGL-1 ,A20291, 20291, SELPLG, P-selectin glycoprotein ligand 1, SELPLG; P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

PSGL-1 Polyclonal Antibody detects endogenous levels of PSGL-1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELPLG. AA range:1-50
Uniprot No

Q14242
Alternative names

SELPLG; P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

selectin P ligand(SELPLG) Homo sapiens This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011],
Other

SELPLG, P-selectin glycoprotein ligand 1
Mol.Wt (Da)

43201
Concentration

1 mg/ml