PSMD1 rabbit pAb

Cat :A20297

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human, Mouse,Rat

  • Dilution

    WB 1:500-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of PSMD1 at Human/Mouse/Rat

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized peptide derived from human PSMD1

  • Uniprot No

    Q99460

  • Alternative names

    26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.225% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2010],

  • Other

    PSMD1, PSMD1

  • Concentration

    1 mg/ml

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