Rabbit
WB
Human, Mouse,Rat
WB 1:500-2000
-20°C/1 year
This antibody detects endogenous levels of PSMD1 at Human/Mouse/Rat
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Synthesized peptide derived from human PSMD1
Q99460
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.225% sodium azide.
Polyclonal
IgG
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2010],
PSMD1, PSMD1
1 mg/ml
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