Rad50 (phospho-Ser635) rabbit pAb

Cat :A20504

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB
Reactivity

Human
Dilution

WB 1:1000-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of Human Rad50 (phospho-Ser635)
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized phosho peptide around human Rad50 (Ser635)
Uniprot No

Q92878
Alternative names

DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

RAD50 double strand break repair protein(RAD50) Homo sapiens The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010],
Other

RAD50, Rad50 (Ser635)
Concentration

1 mg/ml