RASA1 rabbit pAb

Cat :A20583

RASA1 ,A20583, 20583, RASA1 RASA, Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP),

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

H,Rat
Dilution

WB 1:500-2000 ELISA 1:5000-20000
Storage

-20°C/1 year
Specificity

RASA1 Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from part region of human protein
Uniprot No

P20936
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

RAS p21 protein activator 1(RASA1) Homo sapiens The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expres
Other

RASA1 RASA, Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)
Concentration

1 mg/ml