Rb (Acetyl-K873/K874) rabbit pAb

Cat :A20602

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human:K873+K874,Mouse:K866+K867,Rat:K865+K866

  • Dilution

    wb dilution 1:1000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of Rb (Acetyl-K873/K874), It doesn't reacte with total protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized Acetyl peptide derived from human Rb. at AA range: K873/872

  • Uniprot No

    P06400

  • Alternative names

    Retinoblastoma-associated protein (p105-Rb) (pRb) (Rb) (pp110)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    RB transcriptional corepressor 1(RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],

  • Other

    RB1, Rb

  • Concentration

    1 mg/ml

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