RGMC rabbit pAb

Cat :A20755

RGMC ,A20755, 20755, HFE2 HJV RGMC, Hemojuvelin (Hemochromatosis type 2 protein) (RGM domain family member C),

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human,Rat,Mouse
Dilution

WB 1:500-2000 ELISA 1:5000-20000
Storage

-20°C/1 year
Specificity

RGMC Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from human protein . at AA range: 270-350
Uniprot No

Q6ZVN8
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

hemochromatosis type 2 (juvenile)(HFE2) Homo sapiens The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq, Oct 2015],
Other

HFE2 HJV RGMC, Hemojuvelin (Hemochromatosis type 2 protein) (RGM domain family member C)
Concentration

1 mg/ml