RGR rabbit pAb

Cat :A20760

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    IHC,IF,ELISA

  • Reactivity

    Human

  • Dilution

    IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    RGR Polyclonal Antibody detects endogenous levels of RGR protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human RGR. AA range:169-218

  • Uniprot No

    P47804

  • Alternative names

    RGR; RPE-retinal G protein-coupled receptor

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    retinal G protein coupled receptor(RGR) Homo sapiens This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

  • Other

    RGR, RPE-retinal G protein-coupled receptor

  • Mol.Wt (Da)

    31874

  • Concentration

    1 mg/ml

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