Rhotekin rabbit pAb

Cat :A20809

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

IHC: 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Rhotekin Polyclonal Antibody detects endogenous levels of Rhotekin protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from Rhotekin . at AA range: 80-160
Uniprot No

Q9BST9
Alternative names

RTKN; RTKN1; Rhotekin
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

rhotekin(RTKN) Homo sapiens This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Other

RTKN, Rhotekin
Mol.Wt (Da)

62667
Concentration

1 mg/ml