RN213 rabbit pAb

Cat :A20946

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IHC
Reactivity

Human, Mouse
Dilution

IHC 1：50-200
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of RN213 at Human/Mouse
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human RN213
Uniprot No

Q63HN8
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],
Other

RNF213 ALO17 C17orf27 KIAA1554 KIAA1618 MYSTR, RN213
Mol.Wt (Da)

572770
Concentration

1 mg/ml