S2P rabbit pAb

Cat :A21190

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

IF,ELISA
Reactivity

Human,Mouse,Rat
Dilution

IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

S2P Polyclonal Antibody detects endogenous levels of S2P protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human MBTPS2. AA range:301-350
Uniprot No

O43462
Alternative names

MBTPS2; S2P; Membrane-bound transcription factor site-2 protease; Endopeptidase S2P; Sterol regulatory element-binding proteins intramembrane protease; SREBPs intramembrane protease
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

membrane bound transcription factor peptidase, site 2(MBTPS2) Homo sapiens This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009],
Other

MBTPS2, Membrane-bound transcription factor site-2 protease
Mol.Wt (Da)

57444
Concentration

1 mg/ml