SH2B3 rabbit pAb

Cat :A21468

Price： ¥900¥1600

Size： 50ul 100ul

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB 1:500-2000 ELISA 1:5000-20000
Storage

-20°C/1 year
Specificity

SH2B3 Polyclonal Antibody detects endogenous levels of protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthesized peptide derived from part region of human protein
Uniprot No

Q9UQQ2
Form

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

SH2B adaptor protein 3(SH2B3) Homo sapiens This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014],
Other

SH2B3 LNK, SH2B adapter protein 3 (Lymphocyte adapter protein) (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk)
Concentration

1 mg/ml