Smad2/3 (Acetyl-Lys19) rabbit pAb

Cat :A21634

Smad2 ,A21634, 21634, Smad2/3 (Acetyl-Lys19), Smad2/3 (Acetyl-Lys19),

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IHC,WB
Reactivity

Human, Mouse, Rat
Dilution

IHC 1:50-200, WB 1:500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous acetyl levels of Smad2/3 (Acetyl-Lys19) at Human:K19, Mouse:K19, Rat:K19
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human Smad2/3 (Acetyl-Lys19)
Uniprot No

Q15796/P84022
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

SMAD family member 2(SMAD2) Homo sapiens The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation
Other

Smad2/3 (Acetyl-Lys19), Smad2/3 (Acetyl-Lys19)
Concentration

1 mg/ml