SNAT2 rabbit pAb

Cat :A21696

SNAT2 ,A21696, 21696, SLC38A2, Sodium-coupled neutral amino acid transporter 2, SLC38A2; ATA2; KIAA1382; SAT2; SNAT2; Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A a

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

SNAT2 Polyclonal Antibody detects endogenous levels of SNAT2 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human SLC38A2. AA range:151-200
Uniprot No

Q96QD8
Alternative names

SLC38A2; ATA2; KIAA1382; SAT2; SNAT2; Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino a
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

enzyme regulation:Inhibited by N-methyl-D-glucamine and probably choline.,function:Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta.,induction:Up-regulated upon hypertonic conditions and amino acid deprivation.,miscellaneous:Depletion of SCL38A2 by siRNA prevents the recovery of cells from hypertonic stress.,PTM:Polyubiquitination by NEDD4L regulates the degradation and the activity of SLC38A2.,similarity:Belongs to the amino acid/polyamine transporter 2 family.,subcellular location:Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes (By similarity). Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal.,tissue specificity:Ubiquitously expressed. Widely expressed in the central nervous system with higher concentrations in caudal regions. Expressed by glutamatergic and GABAergic neurons together with astrocytes and other non-neuronal cells in the cerebral cortex (at protein level).,
Other

SLC38A2, Sodium-coupled neutral amino acid transporter 2
Mol.Wt (Da)

56026
Concentration

1 mg/ml