SOCS-1 rabbit pAb

Cat :A21727

SOCS,A21727, 21727, SOCS1, Suppressor of cytokine signaling 1, SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IF,WB,IHC,ELISA
Reactivity

Human,Mouse,Rat
Dilution

IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300
Storage

-20°C/1 year
Specificity

SOCS-1 Polyclonal Antibody detects endogenous levels of SOCS-1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human SOCS-1. AA range:49-98
Uniprot No

O15524
Alternative names

SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

suppressor of cytokine signaling 1(SOCS1) Homo sapiens This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008],
Other

SOCS1, Suppressor of cytokine signaling 1
Mol.Wt (Da)

23551
Concentration

1 mg/ml