SPNXA rabbit pAb

Cat :A21832

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    IHC

  • Reactivity

    Human

  • Dilution

    IHC 1:50-200

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of SPNXA at Human

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized peptide derived from human SPNXA

  • Uniprot No

    Q9NS26

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008],

  • Other

    SPANXA1 SPANXA; SPANXA2, SPNXA

  • Mol.Wt (Da)

    10670

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images