SREBP-1 (Acetyl-Lys324) rabbit pAb

Cat :A21892

SREBP,A21892, 21892, SREBF1 BHLHD1 SREBP1, SREBP-1 (Acetyl-Lys324), Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Process

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

IHC,WB
Reactivity

Human, Mouse, Rat
Dilution

IHC 1:50-200, WB 1:500-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous acetyl levels of SREBP-1 (Acetyl-Lys324) at Human:K324, Mouse:K318, Rat:K318
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human SREBP-1 (Acetyl-Lys324)
Uniprot No

P36956
Alternative names

Sterol regulatory element-binding protein 1 (SREBP-1) (Class D basic helix-loop-helix protein 1) (bHLHd1) (Sterol regulatory element-binding transcription factor 1) [Cleaved into: Processed sterol regulatory element-binding protein 1]
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

sterol regulatory element binding transcription factor 1(SREBF1) Homo sapiens This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Mar 2016],
Other

SREBF1 BHLHD1 SREBP1, SREBP-1 (Acetyl-Lys324)
Concentration

1 mg/ml