Stat2 rabbit pAb

Cat :A21992

Price: ¥900¥1600
Size: 50ul 100ul
  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB: 1:500 - 1:2000

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous Stat2 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from human Stat2 around the non-phosphorylation site of Y631.

  • Uniprot No

    P52630

  • Alternative names

    STAT2; Signal transducer and activator of transcription 2; p113

  • Form

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    signal transducer and activator of transcription 2(STAT2) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

  • Other

    STAT2, Signal transducer and activator of transcription 2

  • Concentration

    1 mg/ml

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