Stat3 (phospho-Ser754) rabbit pAb

Cat :A21999

Stat3,A21999, 21999, STAT3 APRF, Stat3 (Ser754), Signal transducer and activator of transcription 3

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB
Reactivity

Human,Mouse
Dilution

WB 1:1000-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of Human Mouse Stat3 (phospho-Ser754)
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized phosho peptide around human Stat3 (Ser754)
Uniprot No

P40763
Alternative names

Signal transducer and activator of transcription 3 (Acute-phase response factor)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

signal transducer and activator of transcription 3(STAT3) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper
Other

STAT3 APRF, Stat3 (Ser754)
Concentration

1 mg/ml