STAT3 mouse mAb(3F4)

Cat :A22002

Stat3,A22002, 22002, STAT3, Signal transducer and activator of transcription 3

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Mouse
Applications

WB,IHC
Reactivity

Human,Rat,Mouse
Dilution

WB 1:1000-2000, IHC 1:100-200
Storage

-20°C/1 year
Specificity

STAT3 protein detects endogenous levels of STAT3
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Recombinant Protein of STAT3
Uniprot No

P40763
Alternative names

STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Monoclonal
Isotype

IgG
Background

signal transducer and activator of transcription 3(STAT3) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper
Other

STAT3, Signal transducer and activator of transcription 3 (Acute-phase response factor)
Concentration

1 mg/ml