STAT5b rabbit pAb

Cat :A22020

Stat5 ,A22020, 22020, STAT5B, Signal transducer and activator of transcription 5B

Price： ¥900¥1600

Size： 50ul 100ul

Datasheet

MSDS

Source

Rabbit
Applications

WB,IHC
Reactivity

Human,Rat,Mouse
Dilution

WB: 1:500-1:2000 IHC: 1:50-1:200
Storage

-20°C/1 year
Specificity

The antibody detects endogenous STAT5b protein
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Recombinant Protein of STAT5b
Uniprot No

P51692
Alternative names

Signal transducer and activator of transcription 5B
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

signal transducer and activator of transcription 5B(STAT5B) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provi
Other

STAT5B, Signal transducer and activator of transcription 5B
Concentration

1 mg/ml